Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906249 | 0.90 | ALDH1A1 (0.43) | PTGDR2LMNAMAPTCTSAKDM4E | |
| SCHEMBL19906366 | 0.89 | CTSA (0.34) | PIK3CGPTGDR2LMNAMAPTCTSA | |
| SCHEMBL19906236 | 0.89 | PTGDR2 (0.38) | PTGDR2CTSAKDM4EALDH1A1MEN1 | |
| SCHEMBL17547091 | 0.85 | EIF4E (0.41) | PTGDR2LMNAMAPTCTSAKDM4E | |
| SCHEMBL19906269 | 0.85 | EIF4E (0.40) | PTGDR2LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL15342558 | 0.84 | CYP3A4 (0.37) | PIK3CGCTSASCN9AAHR | |
| SCHEMBL19905964 | 0.83 | PTGDR2 (0.37) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906329 | 0.83 | KDM4E (0.36) | PTGDR2MAPTCTSAKDM4EALDH1A1 | |
| SCHEMBL19906275 | 0.83 | PTGDR2 (0.37) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906014 | 0.83 | PTGDR2 (0.39) | PIK3CGPTGDR2LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |