Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CTSA | P10619 | 6/20 | 0.36 |
| ▸ | EIF4E | P06730 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19905797 | 0.89 | EIF4E (0.39) | KDM4ECTSAEIF4ELMNAMAPT | |
| SCHEMBL19906322 | 0.87 | CNR1 (0.38) | KDM4ECTSALMNASMN1; SMN2MEN1 | |
| SCHEMBL19906060 | 0.87 | KDM4E (0.38) | KDM4ECTSAEIF4ELMNASMN1; SMN2 | |
| SCHEMBL19906086 | 0.85 | KDM4E (0.39) | KDM4ECTSALMNASMN1; SMN2MAPT | |
| SCHEMBL19906314 | 0.84 | KDM4E (0.40) | KDM4ECTSALMNASMN1; SMN2MEN1 | |
| SCHEMBL19906157 | 0.83 | KDM4E (0.38) | KDM4ECTSALMNASMN1; SMN2MEN1 | |
| SCHEMBL19906323 | 0.82 | SMN1; SMN2 (0.43) | KDM4ECTSALMNASMN1; SMN2MEN1 | |
| SCHEMBL19906366 | 0.82 | CTSA (0.34) | KDM4ECTSALMNASMN1; SMN2MAPT | |
| SCHEMBL19906137 | 0.82 | PTGDR2 (0.39) | KDM4ECTSAEIF4ELMNASMN1; SMN2 | |
| SCHEMBL19906044 | 0.82 | SHMT1 (0.38) | KDM4ECTSALMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |