Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906412 | 0.86 | TP53 (0.38) | MAPTLMNATP53KDM4EPTGDR2 | |
| SCHEMBL19906092 | 0.82 | PTGDR2 (0.48) | MAPTKDM4EPTGDR2ALDH1A1MEN1 | |
| SCHEMBL19906111 | 0.82 | PTGER3 (0.38) | MAPTLMNAKDM4EPTGDR2ALDH1A1 | |
| SCHEMBL19906022 | 0.82 | PTGER3 (0.37) | MAPTLMNAKDM4EPTGDR2ALDH1A1 | |
| SCHEMBL19905990 | 0.81 | GRM5 (0.39) | KDM4EPTGDR2ALDH1A1MEN1KMT2A | |
| SCHEMBL19017855 | 0.81 | PTGDR2 (0.52) | MAPTLMNAKDM4EPTGDR2ALDH1A1 | |
| SCHEMBL19906136 | 0.80 | GRM5 (0.36) | KDM4EPTGDR2ALDH1A1MEN1KMT2A | |
| SCHEMBL19905979 | 0.79 | KDM4E (0.33) | MAPTLMNAKDM4EPTGDR2ALDH1A1 | |
| SCHEMBL19905893 | 0.79 | PTGDR2 (0.41) | MAPTKDM4EPTGDR2ALDH1A1MEN1 | |
| SCHEMBL19905949 | 0.79 | PTGDR2 (0.43) | KDM4EPTGDR2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |