Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.35 |
| ▸ | SHMT1 | P34896 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | EIF4EBP1 | Q13541 | 2/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906129 | 0.90 | EGFR (0.33) | EGFRSHMT1KDM4EPTGDR2IDH1 | |
| SCHEMBL19906017 | 0.90 | KDM4E (0.32) | KDM4EALDH1A1PTGDR2MEN1KMT2A | |
| SCHEMBL19906320 | 0.89 | KDM4E (0.31) | KDM4EALDH1A1PTGDR2MEN1KMT2A | |
| SCHEMBL19906288 | 0.89 | CSF1R (0.35) | EGFRKDM4EALDH1A1PTGDR2MEN1 | |
| SCHEMBL19906374 | 0.88 | POLQ (0.33) | KDM4EALDH1A1PTGDR2MEN1KMT2A | |
| SCHEMBL19906229 | 0.85 | EIF4E (0.36) | SHMT1KDM4EALDH1A1PTGDR2MEN1 | |
| SCHEMBL19906122 | 0.85 | KDM4C (0.34) | KDM4EALDH1A1PTGDR2MEN1KMT2A | |
| SCHEMBL19906268 | 0.85 | EIF4E (0.38) | SHMT1KDM4EALDH1A1PTGDR2MEN1 | |
| SCHEMBL19906145 | 0.85 | KEAP1 (0.34) | KDM4EALDH1A1PTGDR2MEN1KMT2A | |
| SCHEMBL19906126 | 0.85 | KDM4E (0.33) | KDM4EALDH1A1PTGDR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |