Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17826614 | 0.81 | GAA (0.34) | TET2GAARECQL | |
| SCHEMBL24148619 | 0.78 | CA12 (0.41) | GAATSHRALDH1A1TDP1 | |
| SCHEMBL28043538 | 0.77 | ALDH1A1 (0.40) | GAATSHRALDH1A1TDP1 | |
| SCHEMBL23049572 | 0.75 | LMNA (0.33) | GAATSHRALDH1A1TDP1 | |
| SCHEMBL25383365 | 0.73 | ALDH1A1 (0.39) | TSHRALDH1A1TDP1 | |
| SCHEMBL25383367 | 0.72 | ALDH1A1 (0.38) | TSHRALDH1A1TDP1 | |
| SCHEMBL19906319 | 0.71 | GRIN2D (0.32) | TSHRALDH1A1TDP1 | |
| SCHEMBL15499370 | 0.71 | GRIN2D (0.32) | TSHRALDH1A1TDP1 | |
| SCHEMBL363759 | 0.70 | — | — | |
| SCHEMBL24630436 | 0.69 | TDP1 (0.34) | GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890704-B1 | 2'-ETHYNYL NUCLEOSIDE DERIVATIVES FOR TREATMENT OF VIRAL INFECTIONS | NOVARTIS AG (CH) | 2018-02-28 | — | — | EP | disclosed |