Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20732580 | 1.00 | LMNA (0.39) | LMNAHSD17B10DGAT1FDPSALDH1A1 | |
| SCHEMBL9243513 | 0.86 | DGAT1 (0.41) | LMNAHSD17B10DGAT1FDPSALDH1A1 | |
| SCHEMBL28282218 | 0.84 | SMPD1 (0.43) | LMNAFDPSTSHRCYP3A4KDM4E | |
| SCHEMBL28282217 | 0.84 | SMPD1 (0.43) | LMNAFDPSTSHRCYP3A4KDM4E | |
| SCHEMBL21236293 | 0.83 | DGAT1 (0.35) | DGAT1KDM4E | |
| SCHEMBL17617204 | 0.82 | DGAT1 (0.38) | LMNAHSD17B10DGAT1ALDH1A1TSHR | |
| SCHEMBL13317330 | 0.82 | DGAT1 (0.38) | LMNAHSD17B10DGAT1ALDH1A1TSHR | |
| SCHEMBL28911050 | 0.82 | DGAT1 (0.38) | LMNADGAT1ALDH1A1TSHRTDP1 | |
| SCHEMBL9699298 | 0.80 | DGAT1 (0.37) | LMNAHSD17B10DGAT1ALDH1A1TSHR | |
| SCHEMBL31626895 | 0.80 | DGAT1 (0.37) | LMNAHSD17B10DGAT1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2735444-B1 | Lithographic printing plate precursor for newspaper printing and method for producing the same, and plate making method of lithographic printing plate | FUJIFILM CORP (JP) | 2018-02-28 | — | — | EP | disclosed |