Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AOC2 | O75106 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12327373 | 0.89 | AOC3 (0.47) | TAAR1PTGS1PTGS2AOC3HPGD | |
| SCHEMBL11543795 | 0.82 | LMNA (0.53) | LMNATAAR1HSD17B10HPGD | |
| SCHEMBL11443937 | 0.81 | ESR1 (0.55) | LMNATAAR1PTGS1PTGS2HSD17B10 | |
| SCHEMBL2163834 | 0.78 | HDAC1 (0.59) | HPGD | |
| SCHEMBL23003726 | 0.77 | LMNA (0.56) | LMNATAAR1HPGD | |
| SCHEMBL10574057 | 0.77 | TAAR1 (0.62) | TAAR1PTGS1PTGS2AOC3MAOB | |
| SCHEMBL2320532 | 0.77 | TAAR1 (0.62) | TAAR1PTGS1PTGS2AOC3MAOB | |
| SCHEMBL11536859 | 0.76 | NAAA (0.50) | LMNAHSD17B10HPGD | |
| SCHEMBL9253136 | 0.76 | TAAR1 (0.50) | TAAR1PTGS1PTGS2AOC3HPGD | |
| SCHEMBL8271141 | 0.76 | TDP1 (0.48) | LMNATAAR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287443-A1 | 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Shionogi & Co., Ltd (JP) | 2018-02-28 | — | — | EP | disclosed |