Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | EED | O75530 | 1/20 | 0.42 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.42 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.42 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.42 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.42 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19908137 | 0.94 | GPR119 (0.46) | GPR119DPP4TRPV3USP30PRMT5 | |
| SCHEMBL31602551 | 0.94 | GPR119 (0.53) | GPR119DPP4EEDRBBP4SUZ12 | |
| SCHEMBL18183742 | 0.94 | GPR119 (0.53) | GPR119DPP4EEDRBBP4SUZ12 | |
| SCHEMBL31602843 | 0.91 | GPR119 (0.43) | GPR119DPP4EEDRBBP4SUZ12 | |
| SCHEMBL31602655 | 0.90 | GPR119 (0.50) | GPR119DPP4EEDRBBP4SUZ12 | |
| SCHEMBL18183476 | 0.84 | GPR119 (0.47) | GPR119DPP4MMP13 | |
| SCHEMBL20164107 | 0.83 | GPR119 (0.47) | GPR119DPP4USP30PRMT5WDR77 | |
| SCHEMBL20099648 | 0.82 | GPR119 (0.47) | GPR119EEDRBBP4SUZ12EZH2 | |
| SCHEMBL31602599 | 0.82 | GPR119 (0.40) | GPR119DPP4USP30 | |
| SCHEMBL18183477 | 0.81 | GPR119 (0.45) | GPR119DPP4TRPV3USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118750-A1 | IMIDAZO ISOINDOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2018-05-03 | — | — | US | disclosed |
| EP-3287461-A1 | IMIDAZO ISOINDOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2018-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118750-A1 | IMIDAZO ISOINDOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | IDO1, IDO2, TPH1 | GPR119 170/4885DPP4 999/4885EED 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.