Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.47 |
| ▸ | EED | O75530 | 1/20 | 0.45 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.45 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.45 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.45 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20099650 | 0.85 | GPR119 (0.43) | GPR119USP30PRMT5WDR77 | |
| SCHEMBL20099655 | 0.84 | GPR119 (0.45) | GPR119USP30 | |
| SCHEMBL968159 | 0.83 | GPR119 (0.54) | GPR119USP30EEDRBBP4SUZ12 | |
| SCHEMBL1155802 | 0.83 | GPR119 (0.54) | GPR119USP30EEDRBBP4SUZ12 | |
| SCHEMBL1155805 | 0.83 | GPR119 (0.54) | GPR119USP30EEDRBBP4SUZ12 | |
| SCHEMBL1155836 | 0.83 | GPR119 (0.54) | GPR119USP30EEDRBBP4SUZ12 | |
| SCHEMBL1155865 | 0.83 | GPR119 (0.54) | GPR119USP30EEDRBBP4SUZ12 | |
| SCHEMBL1155839 | 0.83 | GPR119 (0.54) | GPR119USP30EEDRBBP4SUZ12 | |
| SCHEMBL1155840 | 0.83 | GPR119 (0.54) | GPR119USP30EEDRBBP4SUZ12 | |
| SCHEMBL19908155 | 0.82 | GPR119 (0.52) | GPR119USP30EEDRBBP4SUZ12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118750-A1 | IMIDAZO ISOINDOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118750-A1 | IMIDAZO ISOINDOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | IDO1, IDO2, TPH1 | GPR119 170/4885USP30 4380/4885EED 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.