Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.52 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1985899 | 1.00 | GABBR2 (0.52) | GABBR2GABBR1TAAR1HTR2AAOC3 | |
| SCHEMBL19734403 | 1.00 | GABBR2 (0.52) | GABBR2GABBR1TAAR1HTR2AAOC3 | |
| SCHEMBL17892059 | 0.88 | CHRNB2 (0.55) | GABBR2GABBR1TAAR1HTR2AAOC3 | |
| SCHEMBL4948330 | 0.88 | HTR2A (0.49) | GABBR2GABBR1TAAR1HTR2AAOC3 | |
| SCHEMBL1263573 | 0.86 | AOC3 (0.48) | TAAR1HTR2AAOC3HRH1LMNA | |
| SCHEMBL28873446 | 0.86 | HTR2A (0.51) | GABBR2GABBR1TAAR1HTR2AHRH1 | |
| SCHEMBL9921479 | 0.85 | HRH1 (0.56) | GABBR2GABBR1TAAR1HTR2AAOC3 | |
| SCHEMBL17484100 | 0.85 | HRH1 (0.56) | GABBR2GABBR1TAAR1HTR2AAOC3 | |
| SCHEMBL11343335 | 0.84 | HTR2A (0.54) | GABBR2GABBR1TAAR1HTR2AHRH1 | |
| SCHEMBL11343665 | 0.84 | HTR2A (0.54) | GABBR2GABBR1TAAR1HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287441-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-28 | — | — | EP | disclosed |