Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053456 | 0.77 | ALDH1A1 (0.67) | ALPLALPGALDH1A1MEN1KMT2A | |
| SCHEMBL19908712 | 0.77 | ALPL (0.47) | ALPLALPGALDH1A1MEN1KMT2A | |
| SCHEMBL11807447 | 0.77 | ALDH1A1 (0.56) | ALPLALPGALDH1A1MEN1KMT2A | |
| SCHEMBL4936082 | 0.76 | MEN1 (0.75) | ALPLALPGALDH1A1MEN1KMT2A | |
| SCHEMBL23469137 | 0.76 | ALPL (0.43) | ALPLALPGALDH1A1MEN1KMT2A | |
| SCHEMBL14311506 | 0.75 | ALDH1A1 (0.64) | ALPLALPGALDH1A1MEN1KMT2A | |
| SCHEMBL3928222 | 0.74 | ALDH1A1 (0.69) | ALPLALPGALDH1A1KMT2AGLA | |
| SCHEMBL11814029 | 0.74 | ALPL (0.53) | ALPLALPGALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9851658 | 0.73 | ALDH1A1 (0.70) | ALPLALPGALDH1A1KMT2AGLA | |
| Bromide SCHEMBL9787677 | 0.73 | ALDH1A1 (0.69) | ALPLALPGALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287441-B1 | ACYLATED 4-AMINOPIPERIDINES AS INHIBITORS OF SERINE PALMITOYLTRANSFERASE | TAKEDA PHARMACEUTICALS CO (JP) | 2021-06-09 | — | — | EP | disclosed |
| EP-3287441-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-28 | — | — | EP | disclosed |