SCHEMBL19908992

SCHEMBL19908992

Cc1cc(C)c(-c2ccc3c(c2)c2ccccc2n3-c2cc(-c3ccncc3)cc(-n3c4ccccc4c4cc(-c5c(C)cc(C)cc5C)ccc43)c2C#N)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE9A O76083 1/20 0.35
PDE1C Q14123 1/20 0.35
MAPK14 Q16539 3/20 0.35
CYP11B2 P19099 1/20 0.34
SQOR Q9Y6N5 1/20 0.34
PTGER4 P35408 1/20 0.32
NPY5R Q15761 1/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
LMNA P02545 2/20 0.31
GAA P10253 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ABL1 P00519 1/20 0.31
PDE10A Q9Y233 2/20 0.31
ADORA1 P30542 1/20 0.31
LRRK2 Q5S007 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19908998 0.95 PDE9A (0.35) PDE9APDE1CMAPK14CYP11B2SQOR
SCHEMBL19908999 0.94 ABL1 (0.34) CYP11B2SQORKDM4EMAPTLMNA
SCHEMBL19913186 0.91 MAPK14 (0.38) PDE9APDE1CMAPK14CYP11B2SQOR
SCHEMBL19913183 0.90 PDE9A (0.39) PDE9APDE1CMAPK14CYP11B2SQOR
SCHEMBL19908994 0.89 ABL1 (0.35) KDM4EMAPTLMNAHTTTDP1
SCHEMBL19909063 0.89 SQOR (0.34) PDE9APDE1CMAPK14CYP11B2SQOR
SCHEMBL19909047 0.88 CYP11B2 (0.38) PDE9APDE1CMAPK14CYP11B2SQOR
SCHEMBL19919739 0.88 PDE9A (0.33) PDE9APDE1CPDE10A
SCHEMBL19908923 0.87 SQOR (0.36) MAPK14CYP11B2SQORPTGER4ALDH1A1
SCHEMBL19909420 0.87 MAPK14 (0.39) PDE9APDE1CMAPK14CYP11B2SQOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 PDE9A 2525/4885PDE1C 4780/4885MAPK14 2544/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 PDE9A 2525/4885PDE1C 4780/4885MAPK14 2544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.