SCHEMBL19909019

SCHEMBL19909019

N#Cc1ccc2c(c1)c1ccccc1n2-c1cc(-c2cc(-c3ccccc3)nc(-c3ccccc3)c2)cc(-n2c3ccccc3c3cc(C#N)ccc32)c1C#N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.43
ABCG2 Q9UNQ0 2/20 0.40
ABCB1 P08183 1/20 0.40
SQOR Q9Y6N5 4/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
ADORA2A P29274 2/20 0.39
ADORA1 P30542 2/20 0.39
MAPK1 P28482 1/20 0.39
JAK2 O60674 1/20 0.38
PRKD3 O94806 1/20 0.38
ABL1 P00519 1/20 0.38
EGFR P00533 1/20 0.38
ERBB2 P04626 1/20 0.38
LCK P06239 1/20 0.38
CDK1 P06493 1/20 0.38
CSF1R P07333 1/20 0.38
LYN P07948 1/20 0.38
RET P07949 1/20 0.38
KIT P10721 1/20 0.38
FGFR1 P11362 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31273681 0.96 MYC (0.45) MYCABCG2ABCB1SQORL3MBTL1
SCHEMBL19909020 0.96 MYC (0.45) MYCABCG2ABCB1SQORL3MBTL1
SCHEMBL19909205 0.92 MYC (0.48) MYCABCG2ABCB1SQORL3MBTL1
SCHEMBL22562515 0.92 ADORA2A (0.40) MYCABCG2ABCB1SQORL3MBTL1
SCHEMBL22563447 0.92 ABCG2 (0.41) ABCG2ABCB1SQORL3MBTL1ADORA2A
SCHEMBL31272893 0.92 SQOR (0.46) MYCSQORL3MBTL1ADORA2AADORA1
SCHEMBL19909154 0.92 SQOR (0.46) MYCSQORL3MBTL1ADORA2AADORA1
SCHEMBL19909400 0.91 ALDH1A3 (0.45) MYCSQORADORA2AADORA1MAPK1
SCHEMBL21278856 0.91 ABCG2 (0.43) ABCG2ABCB1SQORL3MBTL1ADORA2A
SCHEMBL23341359 0.90 SQOR (0.45) MYCSQORL3MBTL1ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 MYC 1697/4885ABCG2 624/4885ABCB1 161/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 MYC 1697/4885ABCG2 624/4885ABCB1 161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.