Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854302 | 0.84 | CYP1A2 (0.56) | CYP1A2ALDH1A1CYP2C19HRH3CYP2D6 | |
| SCHEMBL5573633 | 0.83 | CHRM2 (0.60) | CYP1A2ALDH1A1CYP2C19HRH3CYP2D6 | |
| SCHEMBL6742452 | 0.83 | CYP1A2 (0.60) | MAOAGAACYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL2854495 | 0.81 | KDM4E (0.59) | RAB9ACYP1A2ALDH1A1CYP2C19HRH3 | |
| SCHEMBL6832167 | 0.81 | CYP1A2 (0.55) | CYP1A2ALDH1A1CYP2C19HRH3CYP2D6 | |
| SCHEMBL13778175 | 0.80 | ALDH1A1 (0.56) | NPC1GAARAB9ACYP1A2ALDH1A1 | |
| SCHEMBL15227909 | 0.79 | MAPT (0.67) | GAAALDH1A1LMNACA12CA1 | |
| SCHEMBL1392847 | 0.78 | CHRM2 (0.70) | MAOAMAOBCYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL4923114 | 0.76 | PKM (0.53) | NPC1RAB9ACYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL2932638 | 0.76 | CA12 (0.58) | NPC1GAARAB9ACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776490-B1 | HARDENERS FOR EPOXY RESIN COATINGS | SIKA TECH AG (CH) | 2018-02-28 | — | — | EP | disclosed |