SCHEMBL19909538

SCHEMBL19909538

Cc1ccc2c3ccccc3n(-c3cc(C#N)cc(-n4c5ccccc5c5ccc(C)cc54)c3-c3cc(C)nc(C)c3)c2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE9A O76083 2/20 0.35
PDE1C Q14123 2/20 0.35
PTGER4 P35408 2/20 0.34
HTT P42858 4/20 0.33
LMNA P02545 3/20 0.33
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 3/20 0.33
GAA P10253 3/20 0.33
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
HPGD P15428 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
F2 P00734 1/20 0.32
PLAU P00749 1/20 0.32
ELANE P08246 1/20 0.32
CTRB1 P17538 1/20 0.32
GLA P06280 2/20 0.32
SLC2A1 P11166 1/20 0.32
USP14 P54578 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19913267 0.94 ALDH1A1 (0.35) ALDH1A1SLC2A1USP14GRM2GRM5
SCHEMBL19909545 0.92 PTGER4 (0.36) PDE9APDE1CPTGER4KDM4EALDH1A1
SCHEMBL19913277 0.90 KDM4A (0.35) PDE9APDE1CPTGER4F2PLAU
SCHEMBL19909390 0.90 PTGER4 (0.33) PDE9APDE1CPTGER4LMNAKDM4E
SCHEMBL19913270 0.90 PTGER4 (0.33) PDE9APDE1CPTGER4LMNAKDM4E
SCHEMBL19913286 0.89 IRAK4 (0.34) PDE9APDE1CPTGER4HTTLMNA
SCHEMBL19913282 0.89 PTGER4 (0.39) PDE9APDE1CPTGER4HTTLMNA
SCHEMBL19909110 0.89 IRAK4 (0.33) PDE9APDE1CPTGER4
SCHEMBL19909387 0.89 MEN1 (0.35) PDE9APDE1CPTGER4KDM4EALDH1A1
SCHEMBL22563427 0.88 PTGER4 (0.36) PDE9APDE1CPTGER4HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 PDE9A 2525/4885PDE1C 4780/4885PTGER4 1123/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 PDE9A 2525/4885PDE1C 4780/4885PTGER4 1123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.