Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270031 | 0.82 | ALOX5 (0.54) | ALOX5PTGS2PTGESTDP1L3MBTL1 | |
| SCHEMBL18671367 | 0.80 | HDAC4 (0.48) | ALOX5PTGS2 | |
| SCHEMBL28605004 | 0.78 | ALOX5 (0.54) | ALOX5PTGS2PTGESESR1TDP1 | |
| SCHEMBL19909624 | 0.78 | ALOX5 (0.33) | ALOX5PTGS2PTGESTRPV1 | |
| SCHEMBL18673621 | 0.73 | MTNR1A (0.44) | PTGS2TDP1L3MBTL1 | |
| SCHEMBL18987306 | 0.72 | ALOX5 (0.73) | ALOX5PTGS2PTGESTDP1L3MBTL1 | |
| SCHEMBL13724775 | 0.72 | ALOX5 (0.44) | ALOX5PTGS2PTGESTDP1L3MBTL1 | |
| SCHEMBL22764010 | 0.72 | ERN1 (0.45) | ALOX5PTGS2PTGESTDP1L3MBTL1 | |
| SCHEMBL18342948 | 0.71 | ALOX5 (0.74) | ALOX5PTGS2PTGES | |
| SCHEMBL21558842 | 0.71 | ALOX5 (0.74) | ALOX5PTGS2PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029050-B1 | Bis-phosphites with a naphthyl-phenyl unit as fin component | EVONIK DEGUSSA GMBH (DE) | 2018-02-28 | — | — | EP | disclosed |