SCHEMBL19909701

SCHEMBL19909701

C=C/C=C(\C)C(=O)NCCCCC(NC(=O)c1ccccc1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 15/20 0.47
TGM2 P21980 2/20 0.44
ALB P02768 1/20 0.44
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909787 0.89 FOLH1 (0.48) FOLH1ALBGRIN1GRIN2A
SCHEMBL11544593 0.80 FOLH1 (0.60) FOLH1
SCHEMBL10801036 0.80 FOLH1 (0.60) FOLH1
SCHEMBL11576579 0.79 FOLH1 (0.60) FOLH1
SCHEMBL8975695 0.76 FOLH1 (0.59) FOLH1
SCHEMBL10801725 0.76 FOLH1 (0.59) FOLH1
SCHEMBL1983969 0.76 FOLH1 (0.47) FOLH1ALB
SCHEMBL12560085 0.76 FOLH1 (0.47) FOLH1ALB
SCHEMBL11545905 0.76 NAAA (0.57) FOLH1GRIN1GRIN2A
SCHEMBL24064866 0.74 CA2 (0.63) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3077089-B1 METHOD OF FORMING A COMPOSITE POLYAMIDE MEMBRANE TREATED WITH DIHYROXYARYL COMPOUNDS AND NITROUS ACID DOW GLOBAL TECHNOLOGIES LLC (US) 2018-02-28 EP disclosed