Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140136 | 0.90 | DRD2 (0.42) | DRD2DRD4TMEM97CHRNB2CHRNA4 | |
| SCHEMBL14303649 | 0.87 | DRD2 (0.43) | DRD2DRD4CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL14975544 | 0.80 | MEN1 (0.39) | DRD2DRD4CHRNB4CHRNA3ESR2 | |
| SCHEMBL5467478 | 0.75 | HTR2C (0.37) | — | |
| SCHEMBL6648117 | 0.72 | AR (0.42) | DRD2DRD4TMEM97CHRNB2CHRNA4 | |
| SCHEMBL7684920 | 0.72 | AR (0.42) | DRD2DRD4TMEM97CHRNB2CHRNA4 | |
| SCHEMBL14255888 | 0.71 | ALDH1A1 (0.38) | CHRNB2CHRNA4AR | |
| SCHEMBL17922174 | 0.71 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL14255887 | 0.71 | DRD2 (0.44) | DRD2DRD4CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL12401916 | 0.70 | ESR1 (0.55) | ESR2CYP19A1AROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782916-B1 | CARBOXY X RHODAMINE ANALOGS | PROMEGA CORP (US) | 2018-02-28 | — | — | EP | disclosed |