Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 6/20 | 0.37 |
| ▸ | ZAP70 | P43403 | 4/20 | 0.37 |
| ▸ | CCR4 | P51679 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2007913 | 0.94 | GHSR (0.50) | GHSRSRCZAP70CCR4L3MBTL1 | |
| SCHEMBL1989518 | 0.92 | GHSR (0.48) | GHSRSRCZAP70CCR4L3MBTL1 | |
| SCHEMBL1991756 | 0.90 | GHSR (0.62) | GHSRSRCZAP70CCR4L3MBTL1 | |
| SCHEMBL1990394 | 0.90 | GHSR (0.49) | GHSRSRCZAP70CCR4L3MBTL1 | |
| SCHEMBL1990054 | 0.89 | GHSR (0.54) | GHSRSRCZAP70CCR4L3MBTL1 | |
| SCHEMBL1989861 | 0.87 | GHSR (0.50) | GHSRSRCZAP70CCR4L3MBTL1 | |
| SCHEMBL1986905 | 0.87 | GHSR (0.58) | GHSRL3MBTL1HTR1ASLC6A3 | |
| SCHEMBL1993678 | 0.87 | GHSR (0.48) | GHSRSRCZAP70CCR4L3MBTL1 | |
| SCHEMBL1991288 | 0.86 | GHSR (0.49) | GHSRSRCZAP70CCR4L3MBTL1 | |
| SCHEMBL1996177 | 0.86 | GHSR (0.46) | GHSRSRCZAP70GAAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152232-A1 | SULFONAMIDE COMPOUNDS AND USES THEREOF | SAUNDERS JEFFREY O | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152232-A1 | SULFONAMIDE COMPOUNDS AND USES THEREOF | GHSR, GHRHR, SSTR2 | GHSR 1/4885SRC 2407/4885ZAP70 4029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.