Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.49 |
| ▸ | CCR4 | P51679 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.34 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1989861 | 0.91 | GHSR (0.50) | GHSRCCR4SRCZAP70SCN1A | |
| SCHEMBL1991288 | 0.90 | GHSR (0.49) | GHSRCCR4SRCZAP70SCN1A | |
| SCHEMBL1991024 | 0.90 | GHSR (0.49) | GHSRCCR4SRCZAP70SCN1A | |
| SCHEMBL1990054 | 0.89 | GHSR (0.54) | GHSRCCR4SRCZAP70SCN1A | |
| SCHEMBL1989518 | 0.88 | GHSR (0.48) | GHSRCCR4SRCZAP70SCN1A | |
| SCHEMBL1994348 | 0.88 | GHSR (0.54) | GHSRCCR4SRCZAP70SCN1A | |
| SCHEMBL2007913 | 0.87 | GHSR (0.50) | GHSRCCR4SRCZAP70SCN1A | |
| SCHEMBL1993678 | 0.85 | GHSR (0.48) | GHSRCCR4SRCZAP70L3MBTL1 | |
| SCHEMBL1991756 | 0.85 | GHSR (0.62) | GHSRCCR4SRCZAP70L3MBTL1 | |
| SCHEMBL2004928 | 0.85 | GHSR (0.51) | GHSRCCR4SRCZAP70SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152232-A1 | SULFONAMIDE COMPOUNDS AND USES THEREOF | SAUNDERS JEFFREY O | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152232-A1 | SULFONAMIDE COMPOUNDS AND USES THEREOF | GHSR, GHRHR, SSTR2 | GHSR 1/4885CCR4 4184/4885SRC 2407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.