Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506711 | 0.86 | RAB9A (0.61) | NPC1RAB9ASMN1; SMN2RECQLTSHR | |
| SCHEMBL11325853 | 0.85 | RAB9A (0.63) | NPC1RAB9ASMN1; SMN2RECQLTSHR | |
| SCHEMBL10817231 | 0.79 | RAB9A (0.75) | NPC1RAB9ASMN1; SMN2RECQLTSHR | |
| SCHEMBL17263428 | 0.79 | RAB9A (0.75) | NPC1RAB9ASMN1; SMN2RECQLTSHR | |
| SCHEMBL10597471 | 0.77 | RAB9A (0.77) | NPC1RAB9ASMN1; SMN2RECQLTSHR | |
| SCHEMBL5597234 | 0.76 | RAB9A (0.67) | NPC1RAB9ASMN1; SMN2RECQLTSHR | |
| SCHEMBL14679246 | 0.76 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2RECQLTSHR | |
| SCHEMBL160077 | 0.76 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2RECQLTSHR | |
| SCHEMBL1150814 | 0.75 | RAB9A (0.61) | NPC1RAB9ASMN1; SMN2RECQLTSHR | |
| SCHEMBL96553 | 0.75 | SMN1; SMN2 (0.44) | NPC1RAB9ASMN1; SMN2RECQLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180057450-A1 | NITRILEOXIDE COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057450-A1 | NITRILEOXIDE COMPOUND | NR5A2, NR0B2, NR0B1 | NPC1 2944/4885RAB9A 4231/4885SMN1; SMN2 2711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.