SCHEMBL19912384

SCHEMBL19912384

Cc1cc(-c2cc(-n3c4ccc(C(C)(C)C)cc4c4cc(C(C)(C)C)ccc43)c(C#N)cc2-n2c3ccc(C(C)(C)C)cc3c3cc(C(C)(C)C)ccc32)cc(C(F)(F)F)c1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
AR P10275 2/20 0.32
CSNK1D P48730 1/20 0.31
CSNK1G2 P78368 1/20 0.31
RAPGEF3 O95398 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.31
XDH P47989 1/20 0.31
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19912412 0.96 KIF11 (0.34) TSHRSMN1; SMN2ARKIF11
SCHEMBL19912410 0.96 KIF11 (0.32) TSHRSMN1; SMN2KIF11
SCHEMBL19903496 0.93 RAPGEF3 (0.35) TSHRSMN1; SMN2ARCSNK1DCSNK1G2
SCHEMBL19912425 0.93 KIF11 (0.36) TSHRSMN1; SMN2ARXDHKIF11
SCHEMBL19917907 0.92 KIF11 (0.38) TSHRSMN1; SMN2ARXDHKIF11
SCHEMBL19912387 0.91 AR (0.35) TSHRSMN1; SMN2ARKIF11
SCHEMBL19912407 0.91 KIF11 (0.38) ARKIF11
SCHEMBL22822506 0.90 RXRA (0.36) TSHRSMN1; SMN2CSNK1DCSNK1G2RAPGEF3
SCHEMBL19912570 0.90 KIF11 (0.34) TSHRSMN1; SMN2ARXDHKIF11
SCHEMBL19918034 0.89 KIF11 (0.36) ARRAPGEF3RAPGEF4KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9917270-B1 Organic electroluminescent device having an exciton quenching layer CYNORA GMBH (DE) 2018-03-13 US disclosed
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, AOC3 TSHR 2400/4885SMN1; SMN2 4419/4885AR 4212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.