Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15617678 | 1.00 | ALDH1A1 (0.48) | ALDH1A1LMNAKDM4ETDP1GMNN | |
| SCHEMBL15617674 | 0.90 | ALDH1A1 (0.44) | ALDH1A1LMNAKDM4ETDP1MAPT | |
| SCHEMBL15617673 | 0.88 | HSD11B1 (0.43) | ALDH1A1LMNATDP1KMT2ASMN1; SMN2 | |
| SCHEMBL15617672 | 0.85 | NPC1 (0.58) | ALDH1A1LMNATDP1MAPTSMN1; SMN2 | |
| SCHEMBL15617619 | 0.85 | ACP3 (0.45) | ALDH1A1MAPTKMT2AHSD11B1 | |
| SCHEMBL15617623 | 0.84 | ACP3 (0.44) | ALDH1A1LMNAKDM4ETDP1GMNN | |
| SCHEMBL15617676 | 0.84 | MAPT (0.44) | KDM4EMAPTTSHRHSD11B1 | |
| SCHEMBL15617675 | 0.83 | KMT2A (0.53) | ALDH1A1LMNAKDM4EMAPTKMT2A | |
| SCHEMBL15617671 | 0.82 | HSD11B1 (0.48) | ALDH1A1TDP1SMN1; SMN2HSD11B1ADRA2A | |
| SCHEMBL15617620 | 0.81 | CNR1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10173982-B2 | Picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180057461-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-03-01 | — | — | US | disclosed |
| US-20180057461-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-03-01 | — | — | US | disclosed |
| US-20180057460-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-03-01 | — | — | US | disclosed |
| US-20180057460-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057460-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | ALDH1A1 1130/4885LMNA 4421/4885KDM4E 2568/4885 |
| US-10173982-B2 | Picolinamides as fungicides | CYP1A2, CYP4F12, FKBP2 | ALDH1A1 1130/4885LMNA 4421/4885KDM4E 2568/4885 |
| US-20180057461-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | ALDH1A1 1130/4885LMNA 4421/4885KDM4E 2568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.