SCHEMBL19913178

SCHEMBL19913178

Cc1ccc2c3ccccc3n(-c3cc(-c4ccncc4)cc(-n4c5ccccc5c5ccc(C(F)(F)F)cc54)c3C#N)c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.41
MAT2A P31153 5/20 0.33
PIK3CD O00329 1/20 0.33
CYP11B2 P19099 1/20 0.32
POLB P06746 2/20 0.32
LMNA P02545 2/20 0.32
HIF1A Q16665 2/20 0.32
HTT P42858 1/20 0.32
NCOA1 Q15788 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
DHODH Q02127 1/20 0.32
SQOR Q9Y6N5 1/20 0.32
PDE9A O76083 1/20 0.31
PDE1C Q14123 1/20 0.31
ADORA1 P30542 1/20 0.31
MAPK14 Q16539 1/20 0.31
TP53 P04637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PIK3R2 O00459 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19913184 0.95 KIF11 (0.38) KIF11MAT2APIK3CDPOLBLMNA
SCHEMBL19909345 0.94 KIF11 (0.43) KIF11MAT2APIK3CDCYP11B2SMN1; SMN2
SCHEMBL19913180 0.92 KIF11 (0.36) KIF11CYP11B2POLBLMNAHIF1A
SCHEMBL19909152 0.91 CYP11B2 (0.38) CYP11B2LMNAHIF1ASQORPDE9A
SCHEMBL19913303 0.89 KIF11 (0.42) KIF11MAT2APIK3CDPOLBLMNA
SCHEMBL19909344 0.89 KIF11 (0.44) KIF11MAT2APIK3CDDHODH
SCHEMBL19912530 0.88 KIF11 (0.43) KIF11MAT2APOLBLMNAHIF1A
SCHEMBL19909343 0.88 KIF11 (0.39) KIF11CYP11B2SMN1; SMN2DHODHSQOR
SCHEMBL19913179 0.87 KIF11 (0.38) KIF11POLBLMNAHIF1AHTT
SCHEMBL19913190 0.87 MAPK14 (0.34) KIF11CYP11B2POLBSQORPDE9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed