SCHEMBL19909152

SCHEMBL19909152

Cc1ccc2c3ccccc3n(-c3cc(-c4ccncc4)cc(-n4c5ccccc5c5ccc(C)cc54)c3C#N)c2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 3/20 0.38
SQOR Q9Y6N5 1/20 0.37
PDE9A O76083 1/20 0.36
PDE1C Q14123 1/20 0.36
LMNA P02545 2/20 0.36
TP53 P04637 1/20 0.36
HIF1A Q16665 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ADORA1 P30542 2/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
RECQL P46063 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MAPK14 Q16539 1/20 0.33
THRB P10828 1/20 0.33
ADORA2A P29274 1/20 0.33
PIK3R2 O00459 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909153 0.94 TDP1 (0.35) CYP11B2SQORLMNAADORA1ALDH1A1
SCHEMBL19919473 0.94 PDE9A (0.35) CYP11B2SQORPDE9APDE1CLMNA
SCHEMBL19913187 0.93 PDE9A (0.39) CYP11B2SQORPDE9APDE1CLMNA
SCHEMBL19909047 0.93 CYP11B2 (0.38) CYP11B2SQORPDE9APDE1CLMNA
SCHEMBL19913178 0.91 KIF11 (0.41) CYP11B2SQORPDE9APDE1CLMNA
SCHEMBL19909422 0.90 PIP4K2A (0.40) CYP11B2SQORHIF1AADORA1ALDH1A1
SCHEMBL19908983 0.90 CYP11B2 (0.41) CYP11B2SQORL3MBTL1ADORA1ALDH1A1
SCHEMBL31273507 0.90 CYP11B2 (0.41) CYP11B2SQORL3MBTL1ADORA1ALDH1A1
SCHEMBL19913188 0.90 MAPK14 (0.38) CYP11B2SQORPDE9APDE1CALDH1A1
SCHEMBL19909055 0.90 ABL1 (0.36) CYP11B2SQORPDE9APDE1CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed