SCHEMBL19914058

SCHEMBL19914058

CSc1ccc(Sc2ccc(C=O)cc2)cc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.86
CYP2A6 P11509 3/20 0.46
FBP1 P09467 1/20 0.46
CYP1A1 P04798 3/20 0.44
CYP1A2 P05177 3/20 0.44
CYP1B1 Q16678 3/20 0.44
GSK3B P49841 1/20 0.42
TYR P14679 1/20 0.41
CYP2A13 Q16696 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ALDH5A1 P51649 1/20 0.41
ABAT P80404 1/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41
KMT2A Q03164 2/20 0.40
GAA P10253 2/20 0.40
MAPT P10636 2/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL195687 0.93 ALDH1A1 (1.00) ALDH1A1CYP2A6FBP1CYP1A1CYP1A2
SCHEMBL6853611 0.88 ALDH1A1 (0.64) ALDH1A1CYP2A6TYRCYP2A13HSD17B10
SCHEMBL2149062 0.86 ALDH1A1 (0.86) ALDH1A1CYP2A6FBP1CYP1A1CYP1A2
SCHEMBL2925353 0.85 ALDH1A1 (0.62) ALDH1A1CYP2A6FBP1CYP1A1CYP1A2
SCHEMBL6735568 0.82 CYP2A6 (0.73) ALDH1A1CYP2A6TYRCYP2A13HSD17B10
SCHEMBL28538380 0.81 ALDH1A1 (0.76) ALDH1A1CYP2A6FBP1CYP1A1CYP1A2
SCHEMBL21738358 0.81 ALDH1A1 (0.76) ALDH1A1CYP2A6FBP1CYP1A1CYP1A2
SCHEMBL9264469 0.81 ALDH1A1 (0.76) ALDH1A1CYP2A6FBP1CYP1A1CYP1A2
SCHEMBL7033576 0.80 ALDH1A1 (0.50) ALDH1A1CYP1A1CYP1A2CYP1B1LMNA
Glutaral SCHEMBL5805442 0.79 ALDH1A1 (0.73) ALDH1A1CYP2A6FBP1CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180057635-A1 POLYARYLENE SULFIDE RESIN, METHOD FOR PRODUCING SAME, POLY(ARYLENE SULFONIUM SALT), AND METHOD FOR PRODUCING POLY(ARYLENE SULFONIUM SALT) DIC CORPORATION (JP) 2018-03-01 US disclosed