Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13775167 | 0.95 | SMN1; SMN2 (0.46) | ROCK2MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL21671263 | 0.86 | MEN1 (0.56) | ROCK2MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL26230924 | 0.86 | SMN1; SMN2 (0.44) | ROCK2MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL19915498 | 0.86 | SMN1; SMN2 (0.44) | ROCK2MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL19915501 | 0.83 | NPC1 (0.42) | ROCK2MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL25475919 | 0.81 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL19491612 | 0.80 | KMT2A (0.58) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10255243 | 0.80 | APP (0.44) | ROCK2MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL27104513 | 0.79 | SMN1; SMN2 (0.45) | ROCK2MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL21659099 | 0.79 | KMT2A (0.43) | ROCK2MEN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180055948-A1 | Covalent Linkers in Antibody-Drug Conjugates and Methods of Making and Using the Same | REMEGEN CO., LTD. (CN) | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180055948-A1 | Covalent Linkers in Antibody-Drug Conjugates and Methods of Making and Using the Same | DHFR, FCGR1A, ADCY4 | ROCK2 2403/4885MEN1 3814/4885KMT2A 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.