Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 11/20 | 0.44 |
| ▸ | NPC1 | O15118 | 10/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10533369 | 0.81 | RAB9A (0.47) | PSMB8RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL31314989 | 0.78 | RAB9A (0.52) | PSMB8RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL1233047 | 0.78 | RAB9A (0.52) | PSMB8RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL6414795 | 0.75 | RAB9A (0.48) | PSMB8RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL8491156 | 0.73 | RAB9A (0.49) | PSMB8RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL3083786 | 0.72 | PSMB8 (0.68) | PSMB8RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL3071072 | 0.70 | RAB9A (0.47) | PSMB8RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL11236137 | 0.70 | RAB9A (0.58) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL3071075 | 0.70 | RAB9A (0.47) | PSMB8RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL559230 | 0.70 | RAB9A (0.54) | RAB9ANPC1MAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933841-A | ANTHELMINTICS | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | claimed |
| EP-2338059-B1 | Ligands for aggregated tau molecules | WISTA LAB LTD (SG) | 2015-04-08 | — | — | EP | disclosed |
| US-8895313-B2 | Ligands for aggregated tau molecules | WISTA LABORATORIES LTD. (SG) | 2014-11-25 | — | — | US | disclosed |
| CN-102224423-B | Ligands for aggregated tau molecules | WISTA LABORATORIES LTD. (SG) | 2014-10-22 | — | — | CN | disclosed |
| CN-102224423-A | Ligands for aggregated tau molecules | WISTA LAB LTD | 2011-10-19 | — | — | CN | disclosed |
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. | 2011-07-14 | — | — | US | disclosed |
| EP-2338059-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | Wista Laboratories Ltd. (SG) | 2011-06-29 | — | — | EP | disclosed |
| WO-2010034982-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. (SG) | 2010-04-01 | — | — | WO | disclosed |
| US-4022781-A | ANTHELMINTIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-05-10 | — | — | US | disclosed |
| US-4022781-A | ANTHELMINTIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-05-10 | — | — | US | disclosed |
| US-3985755-A | ANTHELMINTIC AGENTS AND DISINFECTANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3985755-A | ANTHELMINTIC AGENTS AND DISINFECTANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3985755-A | ANTHELMINTIC AGENTS AND DISINFECTANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3983130-A | ANTHELMINTICS, DISINFECTANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-09-28 | — | — | US | disclosed |
| US-3983130-A | ANTHELMINTICS, DISINFECTANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-09-28 | — | — | US | disclosed |
| US-3983130-A | ANTHELMINTICS, DISINFECTANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-09-28 | — | — | US | disclosed |
| US-3969351-A | ANTHELMINTIC | E. R. SQUIBB & SONS, INC. (US) | 1976-07-13 | — | — | US | disclosed |
| US-3969351-A | ANTHELMINTIC | E. R. SQUIBB & SONS, INC. (US) | 1976-07-13 | — | — | US | disclosed |
| US-3969351-A | ANTHELMINTIC | E. R. SQUIBB & SONS, INC. (US) | 1976-07-13 | — | — | US | disclosed |
| US-3934017-A | Anthelmintic composition and method utilizing isothiocyanobenzazoles active ingredients | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | MAPT, PRNP, MAP4 | PSMB8 3217/4885RAB9A 2622/4885NPC1 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.