Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.48 |
| ▸ | NPC1 | O15118 | 11/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1233047 | 0.83 | RAB9A (0.52) | RAB9ANPC1MAPTSMN1; SMN2PSMB8 | |
| SCHEMBL31314989 | 0.83 | RAB9A (0.52) | RAB9ANPC1MAPTSMN1; SMN2PSMB8 | |
| SCHEMBL8491156 | 0.78 | RAB9A (0.49) | RAB9ANPC1MAPTSMN1; SMN2PSMB8 | |
| SCHEMBL3071072 | 0.75 | RAB9A (0.47) | RAB9ANPC1MAPTSMN1; SMN2PSMB8 | |
| SCHEMBL11236137 | 0.75 | RAB9A (0.58) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL559230 | 0.75 | RAB9A (0.54) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL1991644 | 0.75 | PSMB8 (0.46) | RAB9ANPC1MAPTSMN1; SMN2PSMB8 | |
| SCHEMBL3071075 | 0.75 | RAB9A (0.47) | RAB9ANPC1MAPTSMN1; SMN2PSMB8 | |
| SCHEMBL10533369 | 0.75 | RAB9A (0.47) | RAB9ANPC1MAPTSMN1; SMN2PSMB8 | |
| SCHEMBL29531707 | 0.72 | NPC1 (0.69) | RAB9ANPC1MAPTSMN1; SMN2PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286987-B1 | HETEROCYCLIC HYDRAZONES FOR USE AS ANTI-CANCER AGENTS | AUSTRIA WIRTSCHAFTSSERV GMBH (AT) | 2005-09-28 | — | — | EP | disclosed |