Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.58 |
| ▸ | NPC1 | O15118 | 11/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TNF | P01375 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL559230 | 0.81 | RAB9A (0.54) | RAB9ANPC1HPGDTNFL3MBTL1 | |
| SCHEMBL31314989 | 0.78 | RAB9A (0.52) | RAB9ANPC1HPGDTNFL3MBTL1 | |
| SCHEMBL1233047 | 0.78 | RAB9A (0.52) | RAB9ANPC1HPGDTNFL3MBTL1 | |
| SCHEMBL559070 | 0.77 | RAB9A (0.50) | RAB9ANPC1HPGDTNFL3MBTL1 | |
| SCHEMBL22574543 | 0.76 | NPC1 (0.52) | RAB9ANPC1HPGDTNFSMN1; SMN2 | |
| SCHEMBL22467951 | 0.76 | PIK3CG (0.56) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL22468101 | 0.76 | ALDH1A1 (0.59) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL27528127 | 0.75 | RAB9A (0.65) | RAB9ANPC1HPGDTNFL3MBTL1 | |
| SCHEMBL6414795 | 0.75 | RAB9A (0.48) | RAB9ANPC1HPGDTNFL3MBTL1 | |
| SCHEMBL8491156 | 0.73 | RAB9A (0.49) | RAB9ANPC1HPGDTNFL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11952371-B1 | 2-[(1,3-benzoxazol-2-yl)imino]-5,5-diphenylimidazolidin-4-one as an antimicrobial compound | King Faisal University (SA) | 2024-04-09 | — | — | US | claimed |
| US-11952371-B1 | 2-[(1,3-benzoxazol-2-yl)imino]-5,5-diphenylimidazolidin-4-one as an antimicrobial compound | King Faisal University (SA) | 2024-04-09 | — | — | US | disclosed |
| EP-3728211-A1 | BIGUANIDE DERIVATIVES AND THEIR REARRANGEMENT PRODUCTS FOR USE IN THE TREATMENT OF CANCER | Centre National de la Recherche Scientifique (FR) | 2020-10-28 | — | — | EP | disclosed |
| WO-2013043192-A1 | GALACTOKINASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF ASSOCIATED DISEASES AND DISORDERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-03-28 | — | — | WO | disclosed |
| US-4347310-A | INCREASED PHOTOSENZITIVITY USING GUANIDINE DERIVTIVES AS SENSITIZERS; PHOTOSTABILITY; STORAGE STABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1982-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11952371-B1 | 2-[(1,3-benzoxazol-2-yl)imino]-5,5-diphenylimidazolidin-4-one as an antimicrobial compound | MRPL21, NOD1, ZC3HAV1L | RAB9A 3293/4885NPC1 815/4885HPGD 3072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.