Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BPTF | Q12830 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001021 | 0.69 | LMNA (0.35) | LMNASMN1; SMN2TLR7 | |
| SCHEMBL10514950 | 0.65 | LMNA (0.38) | LMNASMN1; SMN2TLR7 | |
| SCHEMBL11880705 | 0.65 | LMNA (0.38) | LMNASMN1; SMN2TLR7 | |
| SCHEMBL7753780 | 0.63 | LMNA (0.52) | LMNASMN1; SMN2BPTF | |
| SCHEMBL22580565 | 0.62 | GLP1R (0.35) | — | |
| SCHEMBL24773616 | 0.62 | LMNA (0.43) | LMNASMN1; SMN2BPTFTLR7 | |
| SCHEMBL4806359 | 0.62 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2TLR7 | |
| SCHEMBL18067288 | 0.62 | LMNA (0.35) | LMNASMN1; SMN2TLR7 | |
| SCHEMBL11509596 | 0.62 | GLP1R (0.38) | LMNASMN1; SMN2TLR7 | |
| SCHEMBL11426170 | 0.60 | PDE10A (0.47) | LMNASMN1; SMN2TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018038265-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | 田辺三菱製薬株式会社 | 2018-03-01 | — | — | WO | disclosed |