Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969628 | 0.81 | KDM4E (0.41) | RAB9AMEN1KMT2AATMTSHR | |
| SCHEMBL30519448 | 0.77 | ALDH1A1 (0.40) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL21123753 | 0.77 | ALDH1A1 (0.40) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL25575417 | 0.77 | RAB9A (0.48) | RAB9AMEN1KMT2AATMSMN1; SMN2 | |
| SCHEMBL21848555 | 0.72 | DDB1 (0.36) | RAB9AMEN1KMT2AATMSMN1; SMN2 | |
| SCHEMBL22027093 | 0.72 | ALDH1A1 (0.39) | MEN1KMT2ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL25544817 | 0.72 | KMT2A (0.42) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL21848395 | 0.70 | GPR119 (0.39) | ATMTSHRKDM4EPOLBPKM | |
| SCHEMBL22027341 | 0.69 | ALDH1A1 (0.37) | MEN1KMT2ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL21848452 | 0.69 | RAB9A (0.39) | RAB9AMEN1KMT2AATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018039232-A1 | METHODS FOR CROSS COUPLING | KALYRA PHARMACEUTICALS, INC. (US) | 2018-03-01 | — | — | WO | disclosed |