Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917588 | 0.96 | TRPA1 (0.40) | ESR2TRPA1NR3C1CYP1A2CYP3A4 | |
| SCHEMBL19917617 | 0.93 | SMN1; SMN2 (0.42) | ESR2TRPA1NR3C1CYP1A2CYP3A4 | |
| SCHEMBL19917533 | 0.93 | AR (0.44) | ESR2TRPA1NR3C1CYP1A2CYP3A4 | |
| SCHEMBL19917517 | 0.91 | ESR2 (0.38) | ESR2TRPA1NR3C1CYP1A2CYP3A4 | |
| SCHEMBL22156667 | 0.90 | NR3C1 (0.42) | ESR2TRPA1NR3C1CYP1A2CYP3A4 | |
| SCHEMBL19917561 | 0.90 | ESR2 (0.38) | ESR2TRPA1NR3C1CYP1A2CYP3A4 | |
| SCHEMBL22898471 | 0.90 | ESR2 (0.38) | ESR2TRPA1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL22155944 | 0.89 | NR3C1 (0.39) | ESR2TRPA1NR3C1CYP1A2CYP3A4 | |
| SCHEMBL19919541 | 0.89 | PDE10A (0.41) | ESR2TRPA1NR3C1CYP1A2CYP3A4 | |
| SCHEMBL22898462 | 0.89 | GRIN1 (0.37) | ESR2TRPA1NR3C1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504200-B1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018037069-A1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2018-03-01 | — | — | WO | disclosed |