Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917593 | 0.93 | ESR2 (0.43) | TRPA1ESR2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19917534 | 0.91 | AR (0.44) | ARTRPA1ESR2ALDH1A1CYP1A2 | |
| SCHEMBL19917535 | 0.90 | AR (0.42) | ARTRPA1ESR2ALDH1A1CYP1A2 | |
| SCHEMBL19917588 | 0.89 | TRPA1 (0.40) | TRPA1ESR2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19917628 | 0.88 | TRPA1 (0.36) | ARTRPA1ESR2ALDH1A1CYP1A2 | |
| SCHEMBL22898471 | 0.88 | ESR2 (0.38) | ARTRPA1ESR2ALDH1A1CYP1A2 | |
| SCHEMBL19917603 | 0.87 | TRPA1 (0.36) | ARTRPA1ESR2ALDH1A1CYP1A2 | |
| SCHEMBL22898462 | 0.87 | GRIN1 (0.37) | TRPA1ESR2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19917606 | 0.86 | GABRG2 (0.39) | TRPA1ESR2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19917617 | 0.86 | SMN1; SMN2 (0.42) | TRPA1ESR2ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504200-B1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018037069-A1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2018-03-01 | — | — | WO | disclosed |