Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 5/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19903452 | 0.97 | PTPN5 (0.37) | PTPN5ARGRIN1GRIN2BALDH1A1 | |
| SCHEMBL25660476 | 0.92 | ALOX5AP (0.38) | PTPN5ARGRIN1GRIN2BALDH1A1 | |
| SCHEMBL20617062 | 0.92 | RXRA (0.38) | PTPN5ARGRIN1GRIN2BALDH1A1 | |
| SCHEMBL19918048 | 0.92 | KIF11 (0.38) | ALDH1A1MAPTSMN1; SMN2TDP1KIF11 | |
| SCHEMBL19903448 | 0.91 | PTPN5 (0.37) | PTPN5ARALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19917620 | 0.89 | KIF11 (0.43) | PTPN5ARGRIN1GRIN2BALDH1A1 | |
| SCHEMBL20617056 | 0.89 | RXRA (0.39) | PTPN5ARGRIN1GRIN2BALDH1A1 | |
| SCHEMBL19917999 | 0.88 | RXRA (0.37) | PTPN5ALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL20617436 | 0.87 | RXRA (0.41) | PTPN5GRIN1GRIN2BALDH1A1MAPT | |
| SCHEMBL19903453 | 0.87 | PTPN5 (0.39) | PTPN5ARALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504200-B1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018037069-A1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2018-03-01 | — | — | WO | disclosed |