Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.34 |
| ▸ | AR | P10275 | 4/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917616 | 0.97 | PTPN5 (0.41) | KIF11PTPN5ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19917621 | 0.93 | PTPN5 (0.39) | KIF11PTPN5ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL25660316 | 0.93 | KIF11 (0.43) | KIF11PTPN5ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21258832 | 0.90 | AR (0.41) | KIF11PTPN5ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19917531 | 0.90 | PTPN5 (0.41) | KIF11PTPN5ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL25658541 | 0.90 | ALOX5AP (0.41) | KIF11PTPN5ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19917601 | 0.89 | PTPN5 (0.37) | KIF11PTPN5ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19917605 | 0.89 | GABRG2 (0.36) | KIF11PTPN5ALDH1A1SMN1; SMN2GABRA1 | |
| SCHEMBL25658546 | 0.89 | ALOX5AP (0.40) | KIF11PTPN5ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL25660237 | 0.89 | KIF11 (0.42) | KIF11ALDH1A1MAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504200-B1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018037069-A1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2018-03-01 | — | — | WO | disclosed |