Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917631 | 0.97 | TRPA1 (0.37) | NR3C1GABRG2GABRB3SMN1; SMN2HIF1A | |
| SCHEMBL21108336 | 0.92 | TRPA1 (0.40) | NR3C1GABRG2GABRB3SMN1; SMN2HIF1A | |
| SCHEMBL19917633 | 0.91 | SMN1; SMN2 (0.41) | NR3C1GABRG2GABRB3SMN1; SMN2HIF1A | |
| SCHEMBL19917568 | 0.90 | SMN1; SMN2 (0.39) | NR3C1GABRG2GABRB3SMN1; SMN2HIF1A | |
| SCHEMBL20114674 | 0.90 | NR3C1 (0.42) | NR3C1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL19917612 | 0.89 | ESR2 (0.40) | NR3C1GABRG2GABRB3SMN1; SMN2HIF1A | |
| SCHEMBL19942792 | 0.89 | ADORA1 (0.40) | SMN1; SMN2HIF1ACYP1A2CYP3A4HSD17B10 | |
| SCHEMBL23487786 | 0.89 | GABRG2 (0.42) | NR3C1GABRG2GABRB3SMN1; SMN2HIF1A | |
| SCHEMBL19917566 | 0.89 | CYP1A2 (0.39) | NR3C1GABRG2GABRB3SMN1; SMN2HIF1A | |
| SCHEMBL21365063 | 0.88 | NR3C1 (0.42) | NR3C1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504200-B1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018037069-A1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2018-03-01 | — | — | WO | disclosed |