Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 19/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917670 | 0.87 | TRPA1 (0.44) | TRPA1 | |
| SCHEMBL19917738 | 0.85 | TRPA1 (0.57) | TRPA1 | |
| SCHEMBL16894126 | 0.84 | TRPA1 (0.71) | TRPA1 | |
| SCHEMBL19917782 | 0.83 | TRPA1 (0.51) | TRPA1PTGES | |
| SCHEMBL19917730 | 0.81 | TRPA1 (0.44) | TRPA1 | |
| SCHEMBL19917696 | 0.80 | TRPA1 (0.48) | TRPA1 | |
| SCHEMBL19917691 | 0.79 | KDM1A (0.45) | TRPA1 | |
| SCHEMBL19917662 | 0.79 | TRPA1 (0.43) | TRPA1 | |
| SCHEMBL19917703 | 0.78 | TRPA1 (0.51) | TRPA1PTGES | |
| SCHEMBL19917750 | 0.78 | TRPA1 (0.53) | TRPA1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900642-B1 | SUBSTITUTED SULFONAMIDE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-02-28 | — | — | EP | disclosed |