SCHEMBL19918554

SCHEMBL19918554

c1ccc(-c2nc(-n3c4ccc(-c5ccc6oc7ccccc7c6c5)cc4c4c5cccc6c5c(cc43)-c3ccccc3-6)nc3ccc4ccccc4c23)cc1

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CYP1A1 P04798 1/20 0.30
CYP1A2 P05177 1/20 0.30
FYN P06241 1/20 0.30
MAPK3 P27361 1/20 0.30
AHR P35869 1/20 0.30
PAX8 Q06710 1/20 0.30
ABCG2 Q9UNQ0 1/20 0.30
CYP2A6 P11509 1/20 0.30
SIRT2 Q8IXJ6 1/20 0.30
SIRT1 Q96EB6 1/20 0.30
PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19918555 0.99 KDM4E (0.31) KDM4EALDH1A1MAPTHPGDALOX15
SCHEMBL19918490 0.92 KDM4E (0.31) KDM4EALDH1A1MAPTHPGDCYP1A1
SCHEMBL19918682 0.89 PTGES (0.35) KDM4EALDH1A1MAPTHPGDCYP1A1
SCHEMBL19918548 0.88 MAPK1 (0.32) KDM4EALDH1A1MAPTHPGDALOX15
SCHEMBL19918426 0.88 ALDH1A1 (0.32) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL19918558 0.87 MAPK1 (0.31) KDM4EALDH1A1MAPTHPGDALOX15
SCHEMBL19918427 0.87 ALDH1A1 (0.32) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL19918627 0.86 PTGES (0.36) KDM4EALDH1A1MAPTHPGDPTGES
SCHEMBL19918467 0.86 PTGES (0.36) KDM4EALDH1A1MAPTHPGDPTGES
SCHEMBL19918716 0.85 PTGES (0.35) KDM4EALDH1A1MAPTHPGDPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018038400-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING SAME 주식회사 두산 2018-03-01 WO disclosed