SCHEMBL19918490

SCHEMBL19918490

c1ccc(-c2ccc(-c3nc(-n4c5ccc(-c6ccc7oc8cc9c%10c(cccc%10c8c7c6)-c6ccccc6-9)cc5c5c6ccccc6ccc54)nc4ccc5ccccc5c34)cc2)cc1

nearest known ligand 0.31

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
CYP1A1 P04798 1/20 0.30
CYP1A2 P05177 1/20 0.30
FYN P06241 1/20 0.30
MAPK3 P27361 1/20 0.30
AHR P35869 1/20 0.30
PAX8 Q06710 1/20 0.30
ABCG2 Q9UNQ0 1/20 0.30
PIK3CD O00329 1/20 0.30
PIK3CA P42336 1/20 0.30
PIK3CB P42338 1/20 0.30
MTOR P42345 1/20 0.30
PIK3CG P48736 1/20 0.30
PTGES O14684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19918682 0.94 PTGES (0.35) KDM4EALDH1A1MAPTHPGDCYP1A1
SCHEMBL19918555 0.92 KDM4E (0.31) KDM4EALDH1A1MAPTHPGDCYP1A1
SCHEMBL19918554 0.92 KDM4E (0.31) KDM4EALDH1A1MAPTHPGDCYP1A1
SCHEMBL19918481 0.91 KDM4E (0.31) KDM4EALDH1A1MAPTHPGD
SCHEMBL19918485 0.90 KDM4E (0.32) KDM4EALDH1A1MAPTHPGD
SCHEMBL19918427 0.87 ALDH1A1 (0.32) KDM4EALDH1A1MAPTHPGDPTGES
SCHEMBL19918491 0.87
SCHEMBL19918480 0.87 L3MBTL1 (0.31) KDM4EALDH1A1HPGD
SCHEMBL19918426 0.86 ALDH1A1 (0.32) KDM4EALDH1A1MAPTHPGDPIK3CD
SCHEMBL19918683 0.85 ALDH1A1 (0.37) KDM4EALDH1A1MAPTHPGDPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018038400-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING SAME 주식회사 두산 2018-03-01 WO disclosed