Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185360 | 0.81 | GAA (0.46) | GAAKDM4EHPGDL3MBTL1MEN1 | |
| SCHEMBL2789941 | 0.78 | GAA (0.73) | GAAKDM4EHPGDIKBKBKMT2A | |
| Hydrochloric Acid SCHEMBL11623044 | 0.77 | GAA (0.71) | GAAKDM4EHPGDIKBKBKMT2A | |
| SCHEMBL5013672 | 0.71 | GAA (0.68) | GAAKDM4EHPGDIKBKBALDH1A1 | |
| SCHEMBL7894439 | 0.71 | GAA (0.40) | GAAKDM4EIKBKBALDH1A1LMNA | |
| SCHEMBL31301354 | 0.70 | GAA (0.58) | GAAKDM4EHPGDIKBKBMEN1 | |
| SCHEMBL2186221 | 0.70 | ALDH1A1 (0.52) | GAAKDM4EHPGDL3MBTL1MEN1 | |
| SCHEMBL20646882 | 0.69 | GAA (0.69) | GAAKDM4EIKBKBALDH1A1LMNA | |
| SCHEMBL17613621 | 0.69 | ACMSD (0.66) | GAAKDM4EHPGDMEN1KMT2A | |
| SCHEMBL2792622 | 0.68 | IKBKB (0.57) | GAAKDM4EHPGDIKBKBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343279-B1 | FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME | KISSEI PHARMACEUTICAL (JP) | 2018-02-28 | — | — | EP | disclosed |