Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | IKBKB | O14920 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789941 | 0.88 | GAA (0.73) | GAAIKBKBKDM4EHSD17B10PPARG | |
| Hydrochloric Acid SCHEMBL11623044 | 0.86 | GAA (0.71) | GAAIKBKBKDM4EHSD17B10PPARG | |
| SCHEMBL11626804 | 0.85 | IKBKB (0.55) | GAAIKBKBKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL20646882 | 0.85 | GAA (0.69) | GAAIKBKBKDM4EHSD17B10PPARG | |
| SCHEMBL2775125 | 0.83 | GAA (0.68) | GAAIKBKBKDM4EHSD17B10PPARG | |
| SCHEMBL11624706 | 0.83 | GAA (0.76) | GAAIKBKBKDM4EHSD17B10PPARG | |
| SCHEMBL4741742 | 0.81 | IKBKB (0.57) | GAAIKBKBKDM4EHSD17B10PPARG | |
| SCHEMBL11620116 | 0.81 | GAA (0.78) | GAAIKBKBKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL20646881 | 0.81 | GAA (0.64) | GAAIKBKBKDM4EHSD17B10PPARG | |
| SCHEMBL2778196 | 0.81 | ALDH1A1 (0.74) | GAAKDM4EHSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884513-A1 | PYRAZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES COMPRISING THE SAME | Japan Tobacco, Inc. (JP) | 2008-02-06 | — | — | EP | claimed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | claimed |
| US-4072689-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1978-02-07 | — | — | US | claimed |
| EP-1884513-A1 | PYRAZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES COMPRISING THE SAME | Japan Tobacco, Inc. (JP) | 2008-02-06 | — | — | EP | disclosed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
| US-4072689-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | PYGL, GYS2, AGL | GAA 53/4885IKBKB 2703/4885KDM4E 3446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.