Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1991256 | 0.96 | SMN1; SMN2 (0.61) | SMN1; SMN2L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL1070289 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL1067810 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL1068543 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL7762856 | 0.77 | TNKS2 (0.43) | SMN1; SMN2L3MBTL1LMNATP53 | |
| SCHEMBL11277506 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL16915719 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1LMNATP53ACHE | |
| SCHEMBL1992827 | 0.72 | L3MBTL1 (0.47) | SMN1; SMN2L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL1990556 | 0.68 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL30015888 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | SMN1; SMN2 2548/4885L3MBTL1 3898/4885ALDH1A1 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.