Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9169236 | 0.83 | TRPA1 (0.61) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL22137732 | 0.83 | TRPA1 (0.47) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL11138508 | 0.82 | LMNA (0.59) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL30893081 | 0.82 | LMNA (0.64) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL4401739 | 0.82 | LMNA (0.64) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL29492305 | 0.81 | TYR (0.48) | BCHETYRACHE | |
| SCHEMBL21830477 | 0.81 | TYR (0.48) | BCHETYRACHE | |
| SCHEMBL29477946 | 0.80 | LMNA (0.62) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL9461044 | 0.80 | LMNA (0.57) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Potassium SCHEMBL29477939 | 0.80 | LMNA (0.62) | TRPA1LMNACHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334175-A2 | PHENYL-SUBSTITUTED BICYCLOOCTANE-1,3-DIONE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010040460-A2 | PHENYL-SUBSTITUTED BICYCLOOCTANE-1,3-DIONE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-04-15 | — | — | WO | disclosed |