Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28897192 | 0.90 | ELANE (0.38) | KMT2AELANEPRTN3PKMMEN1 | |
| SCHEMBL14487909 | 0.78 | ELANE (0.38) | KMT2AELANEPRTN3PKMALDH1A1 | |
| SCHEMBL16318681 | 0.76 | ALDH1A1 (0.37) | ELANEPRTN3ALDH1A1CA1CA2 | |
| SCHEMBL22260778 | 0.73 | PTPN11 (0.37) | ELANEPRTN3PKMHTTPOLB | |
| SCHEMBL16207740 | 0.72 | CA1 (0.37) | ELANEPRTN3MMP2TSHRCA1 | |
| SCHEMBL18951969 | 0.70 | CA1 (0.49) | KMT2APKMMEN1HTTALDH1A1 | |
| SCHEMBL4441787 | 0.70 | CYP2C9 (0.41) | KMT2AMEN1MMP2POLBTSHR | |
| SCHEMBL31369076 | 0.70 | KDM4E (0.39) | ELANEPRTN3CA1CA2 | |
| SCHEMBL17518589 | 0.68 | JAK2 (0.35) | KMT2AELANEPRTN3PKMTSHR | |
| SCHEMBL17518496 | 0.67 | JAK2 (0.35) | ELANEPRTN3PKMPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180065962-A1 | METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065962-A1 | METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION | POLRMT, POLM, POLR2H | KMT2A 1075/4885ELANE 2866/4885PRTN3 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.