Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | EDNRA | P25101 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | GLB1 | P16278 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147535 | 0.83 | PTGS2 (0.59) | PTGS2HDAC4HDAC10HDAC6HDAC5 | |
| SCHEMBL15499628 | 0.81 | HDAC4 (0.59) | PTGS2HDAC4HDAC10HDAC6HDAC5 | |
| SCHEMBL18994878 | 0.80 | PTGS2 (0.60) | PTGS2HDAC4HDAC10HDAC6HDAC5 | |
| SCHEMBL9832298 | 0.80 | ALDH1A1 (0.41) | PTGS2NPC1TP53CYP3A4CYP2D6 | |
| SCHEMBL15498139 | 0.79 | EDNRA (0.57) | PTGS2HDAC4HDAC10HDAC6HDAC5 | |
| SCHEMBL15743869 | 0.79 | HDAC4 (0.57) | PTGS2HDAC4HDAC10HDAC6HDAC5 | |
| SCHEMBL4126957 | 0.78 | HDAC4 (0.71) | HDAC4HDAC10HDAC6HDAC5EDNRA | |
| SCHEMBL4139459 | 0.78 | HDAC4 (0.75) | HDAC4HDAC10HDAC6HDAC5EDNRA | |
| SCHEMBL15499622 | 0.78 | HDAC4 (0.56) | PTGS2HDAC4HDAC10HDAC6HDAC5 | |
| SCHEMBL12686661 | 0.77 | HDAC4 (0.57) | PTGS2HDAC4HDAC10HDAC6HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10723760-B2 | Method for preparing site-specifically modified protein based on novel carbon-carbon bond formation | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-07-28 | — | — | US | disclosed |
| WO-2018044130-A1 | NOVEL METHOD FOR PRODUCING PROTEIN HAVING A CARBON-CARBON BOND-BASED SITE-SPECIFIC MODIFICATION | 한국과학기술원 | 2018-03-08 | — | — | WO | disclosed |
| US-20180066011-A1 | METHOD FOR PREPARING SITE-SPECIFICALLY MODIFIED PROTEIN BASED ON NOVEL CARBON-CARBON BOND FORMATION | PROMEDIGEN (KR) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10723760-B2 | Method for preparing site-specifically modified protein based on novel carbon-carbon bond formation | PTMS, CHAMP1, STUB1 | PTGS2 3646/4885HDAC4 3545/4885HDAC10 3006/4885 |
| US-20180066011-A1 | METHOD FOR PREPARING SITE-SPECIFICALLY MODIFIED PROTEIN BASED ON NOVEL CARBON-CARBON BOND FORMATION | PTMS, CHAMP1, STUB1 | PTGS2 3646/4885HDAC4 3545/4885HDAC10 3006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.