Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.60 |
| ▸ | DPP4 | P27487 | 5/20 | 0.60 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.60 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.60 |
| ▸ | FAP | Q12884 | 2/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19922947 | 1.00 | DPP7 (0.60) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL2376093 | 0.85 | HDAC8 (0.59) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL2376087 | 0.85 | HDAC8 (0.59) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL19923019 | 0.85 | HPN (0.50) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL19923016 | 0.85 | HPN (0.50) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL19923030 | 0.84 | DPP7 (0.61) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL19923028 | 0.84 | DPP7 (0.61) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL8385358 | 0.84 | DPP7 (0.72) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL18049265 | 0.83 | DPP7 (0.57) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL18049261 | 0.83 | DPP7 (0.57) | DPP7DPP4DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169676-A1 | INHIBITORS OF GROWTH FACTOR ACTIVATION ENZYMES | WASHINGTON UNIVERSITY (US) | 2022-06-02 | — | — | US | disclosed |
| US-11130780-B2 | Inhibitors of growth factor activation enzymes | WASHINGTON UNIVERSITY (US) | 2021-09-28 | — | — | US | disclosed |
| US-20180066015-A1 | INHIBITORS OF GROWTH FACTOR ACTIVATION ENZYMES | WASHINGTON UNIVERSITY (US) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11130780-B2 | Inhibitors of growth factor activation enzymes | HDGF, MMP7, HGF | DPP7 354/4885DPP4 682/4885DPP8 334/4885 |
| US-20220169676-A1 | INHIBITORS OF GROWTH FACTOR ACTIVATION ENZYMES | HDGF, MMP7, HGF | DPP7 354/4885DPP4 682/4885DPP8 334/4885 |
| US-20180066015-A1 | INHIBITORS OF GROWTH FACTOR ACTIVATION ENZYMES | HDGF, MMP7, HGF | DPP7 354/4885DPP4 682/4885DPP8 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.