SCHEMBL19923609

SCHEMBL19923609

O=C1N(c2ccccc2)C(=O)C(c2ccccc2)(c2ccccc2)N1[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.40
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
MGLL Q99685 1/20 0.35
PGR P06401 1/20 0.33
GRK5 P34947 1/20 0.33
TYRO3 Q06418 1/20 0.33
DYRK1B Q9Y463 1/20 0.33
HTR1A P08908 1/20 0.32
HTR7 P34969 1/20 0.32
HTR6 P50406 1/20 0.32
CNR1 P21554 1/20 0.32
ITGA4 P13612 1/20 0.32
ITGB7 P26010 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923558 0.85 ELANE (0.41) ELANESMN1; SMN2ALDH1A1GAAMGLL
SCHEMBL19923430 0.83 ELANE (0.45) ELANESMN1; SMN2ALDH1A1LMNAGAA
SCHEMBL19923498 0.81 ALDH1A1 (0.36) ALDH1A1LMNA
SCHEMBL19923489 0.79 ELANE (0.42) ELANESMN1; SMN2ALDH1A1LMNAGAA
SCHEMBL19923532 0.79 ELANE (0.49) ELANESMN1; SMN2ALDH1A1LMNAGAA
SCHEMBL19923685 0.79 ELANE (0.49) ELANELMNA
SCHEMBL19923463 0.75 ELANE (0.46) ELANESMN1; SMN2ALDH1A1LMNAGAA
SCHEMBL19923766 0.72 ELANE (0.44) ELANESMN1; SMN2ALDH1A1GAAMGLL
SCHEMBL19923491 0.72 ALDH1A1 (0.34) ELANEALDH1A1GAAHTR1AHTR7
SCHEMBL19923536 0.70 ELANE (0.49) ELANESMN1; SMN2ALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN ELANE 1249/4885SMN1; SMN2 1697/4885ALDH1A1 2648/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM ELANE 1276/4885SMN1; SMN2 1924/4885ALDH1A1 2554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.