SCHEMBL19923641

SCHEMBL19923641

CCC[Si](CCC)(CCC)N1C(=O)N(C)C(CC)(c2ccccc2)C1=O

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MITF O75030 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP2C19 P33261 2/20 0.39
TSHR P16473 1/20 0.39
LMNA P02545 2/20 0.38
PKM P14618 1/20 0.36
BACE1 P56817 2/20 0.35
BACE2 Q9Y5Z0 2/20 0.35
ELANE P08246 1/20 0.34
REN P00797 1/20 0.34
APP P05067 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
FAAH O00519 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923427 0.90 MITF (0.41) MITFMEN1KMT2ACYP2C19TSHR
SCHEMBL19923578 0.86 MITF (0.40) MITFMEN1KMT2ACYP2C19TSHR
SCHEMBL19923592 0.85 MITF (0.42) MITFMEN1KMT2ACYP2C19TSHR
SCHEMBL19923717 0.84 MITF (0.39) MITFMEN1KMT2ACYP2C19TSHR
SCHEMBL19923729 0.83 MITF (0.39) MITFMEN1KMT2ACYP2C19TSHR
SCHEMBL19923541 0.83 ELANE (0.39) MITFMEN1KMT2ACYP2C19TSHR
SCHEMBL19923734 0.82 TSHR (0.38) MEN1KMT2ACYP2C19TSHRLMNA
SCHEMBL19923742 0.81 NPSR1 (0.43) MITFMEN1KMT2ACYP2C19LMNA
SCHEMBL19923407 0.81 TSHR (0.37) MEN1KMT2ACYP2C19TSHRLMNA
SCHEMBL17794057 0.79 CYP2C19 (0.49) MITFMEN1KMT2ACYP2C19TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN MITF 4251/4885MEN1 2213/4885KMT2A 1080/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM MITF 4361/4885MEN1 2164/4885KMT2A 999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.