SCHEMBL19923635

SCHEMBL19923635

O=C1N(Cc2ccccc2)C(=O)C(c2ccccc2)(c2ccccc2)N1Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.53
CTSG P08311 2/20 0.53
F2 P00734 1/20 0.53
PLG P00747 1/20 0.53
CMA1 P23946 1/20 0.53
CTRC Q99895 1/20 0.53
NPSR1 Q6W5P4 2/20 0.53
CYP2C19 P33261 3/20 0.47
GSK3A P49840 1/20 0.46
GSK3B P49841 1/20 0.46
MGLL Q99685 1/20 0.46
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
PRTN3 P24158 1/20 0.44
EP300 Q09472 1/20 0.42
CNR1 P21554 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5439673 0.90 ELANE (0.46) ELANECTSGF2PLGCMA1
SCHEMBL14372430 0.89 NPSR1 (0.49) ELANECTSGF2PLGCMA1
SCHEMBL5432681 0.89 ELANE (0.44) ELANECTSGF2PLGCMA1
SCHEMBL15461432 0.82 OPRM1 (0.46) ELANECTSGF2PLGCMA1
SCHEMBL19923680 0.81 ELANE (0.56) ELANECTSGF2PLGCMA1
SCHEMBL5438240 0.79 ELANE (0.45) ELANECTSGF2PLGCMA1
SCHEMBL19923755 0.78 NPSR1 (0.59) ELANECTSGF2PLGCMA1
SCHEMBL19923487 0.78 ELANE (0.41) ELANECTSGF2PLGCMA1
SCHEMBL19923520 0.78 ELANE (0.61) ELANECTSGF2PLGCMA1
SCHEMBL19923500 0.77 ELANE (0.39) ELANECTSGF2PLGCMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN ELANE 1249/4885CTSG 1654/4885F2 1194/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM ELANE 1276/4885CTSG 1736/4885F2 1255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.